Low-dose methotrexate-induced vulvar edema

Low-dose methotrexate-induced ulcerated psoriatic plaques: A rare case.

INTRODUCTION Low-dose methotrexate is an effective and safe management for extensive and severe psoriasis. It may cause adverse reactions ranging from trivial to life threatening. Among them, hepatotoxicity and pancytopenia are the common serious side effects, whereas painful ulceration of psoriatic plaques as an early cutaneous manifestation of low-dose methotrexate toxicity has rarely been re...

Low dose Methotrexate for the treatment of generalized lichen planus

Background: Lichen planus is a common inflammatory disease that can involve the skin, nails, mucous membrane, and hair follicles. There is a long list of topical and systemic therapies for its treatment. Methotrexarte has some characteristics that make it a good choice for generalized lichen planus. Aim: The goal of this study was to assess the effect of low dose methotrexate in generalized lic...

Low-dose methotrexate in myeloproliferative neoplasm models.

Low-dose radiotherapy for primary cutaneous anaplastic large-cell lymphoma while on low-dose methotrexate.

Primary cutaneous anaplastic large-cell lymphoma (pcALCL) is part of a spectrum of CD30+ primary cutaneous lymphoproliferative disorders (pcLPDs) that also includes lymphomatoid papulosis (LyP). Localized radiotherapy at doses of 34 to 44 Gy is first-line treatment of pcALCL, but the use of low-dose radiotherapy for pcALCL has not been reported. We present the case of a patient with a history o...

Pneumocystis jirovecii pneumonia induced by low-dose methotrexate in a patient with chronic urticaria*

Methotrexate has immunosuppressive effects and is administered for refractory chronic urticaria. We present a case of Pneumocystis jirovecii pneumonia in a patient with refractory chronic urticaria managed by low-dose weekly methotrexate treatment (total cumulative dose 195mg). Our study highlights the importance of providing prompt diagnosis and treatment of Pneumocystis jirovecii pneumonia in...